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The art of drug synthesis
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The art of drug synthesis

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Contents

The role of medicinal chemistry in drug discovery / John A. Lowe III
Process research: how much? how soon? / Neal G. Anderson
Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li
Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis
Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell
Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms
Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li
Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li
Angiotensin AT1 antagonists for hypertension / Larry Yet
Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava
Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen
Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn
Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum
Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez
GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo
Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen
Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray.

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The art of drug synthesis. ISBN 9780471752158. Published by John Wiley in 2007. Publication and catalogue information, links to buy online and reader comments.

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